Article
Cytokine responses of peripheral blood mononuclear cells to allergen do not identify asthma or asthma phenotypes.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Nov 2013
Simms E, Kjarsgaard M, Denis S, Hargreave F E, Nair P, Larché M
Abstract excerpt
BACKGROUND: Asthmatic patients are often differentiated based on their atopic status (atopic or nonatopic) and type of bronchitis (eosinophilic, neutrophilic, both, or neither). There is evidence supporting a central role for the T cell in asthma, but the role of allergen-induced T cell cytokines in driving disease in different asthma phenotypes remains unclear. OBJECTIVE: To investigate the hypothesis that...
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