Article
Diagnosing fatty liver disease: a comparative evaluation of metabolic markers, phenotypes, genotypes and established biomarkers.
PloS one - 1 Jan 2013
Siegert Sabine, Yu Zhonghao, Wang-Sattler Rui, Illig Thomas, Adamski Jerzy, Hampe Jochen, Nikolaus Susanna, Schreiber Stefan, Krawczak Michael, Nothnagel Michael, Nöthlings Ute
Abstract excerpt
BACKGROUND: To date, liver biopsy is the only means of reliable diagnosis for fatty liver disease (FLD). Owing to the inevitable biopsy-associated health risks, however, the development of valid noninvasive diagnostic tools for FLD is well warranted. AIM: We evaluated a particular metabolic profile with regard to its ability to diagnose FLD and compared its performance to that of established phenotypes,...
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