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Article

Targeting Neuroblastoma Stem Cells with Retinoic Acid and Proteasome Inhibitor

7 Oct 2013

Abstract excerpt

BACKGROUND: Neuroblastma cell lines contain a side-population of cells which express stemness markers. These stem-like cells may represent the potential underlying mechanism for resistance to conventional therapy and recurrence of neuroblastoma in patients. METHODOLOGY/PRINCIPAL FINDINGS: To develop novel strategies for targeting the side-population of neurobastomas, we analyzed the effects of 13-cis-retinoic...

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PMID: 24116151
DOI: 10.1371/journal.pone.0076761

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