Genomic Identification of Potential Targets Unique to Candida albicans for the Discovery of Antifungal Agents

Abstract excerpt

Despite of modern antifungal therapy, the mortality rates of invasive infection with human fungal pathogen Candida albicans are up to 40%. Studies suggest that drug resistance in the three most common species of human fungal pathogens viz., C. albicans, Aspergillus fumigatus (causing mortality rate up to 90%) and Cryptococcus neoformans (causing mortality rate up to 70%) is due to mutations in the target enzymes...

Topics

Join the communities discussing this publication.

• Antifungal resistance and susceptibility
• Peptidase Inhibition and Analysis
• vaccines and immunoinformatics approaches