Article
An empirical test of convergent evolution in rhodopsins.
Molecular biology and evolution - 1 Jan 2014
Mackin Kristine A, Roy Richard A, Theobald Douglas L
Abstract excerpt
Rhodopsins are photochemically reactive membrane proteins that covalently bind retinal chromophores. Type I rhodopsins are found in both prokaryotes and eukaryotic microbes, whereas type II rhodopsins function as photoactivated G-protein coupled receptors (GPCRs) in animal vision. Both rhodopsin families share the seven transmembrane α-helix GPCR fold and a Schiff base linkage from a conserved lysine to retinal...
Topics
- Archaeal Proteins
- Evolution, Molecular
- Gene Expression
- Halobacteriaceae
- Membrane Proteins
- Mutation
- Protein Folding
- Protein Structure, Secondary
- Rhodopsin