Article
Association between the TRAIL single nucleotide polymorphism rs1131580 and type 2 diabetes mellitus in a Han Chinese population.
Genetics and molecular research : GMR - 10 Sept 2013
Yu M Y, Zhao P Q, Yan X H, Liu B, Zhang Q Q, Wang R, Ma C H, Liang X H, Zhu F L, Gao L F
Abstract excerpt
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is expressed in different tissues and cells, including the pancreas and lymphocytes, and it can selectively induce apoptosis in tumor cells but not in most normal cells. TRAIL plays critical roles in type 1 diabetes mellitus, a...
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