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Article

Treatment of Niemann–Pick Type C Disease by Histone Deacetylase Inhibitors

18 Sept 2013

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 24048860
DOI: 10.1007/s13311-013-0217-2

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Treatment of Niemann–Pick Type C Disease by Histone Deacetylase InhibitorsPMID 24048860Read ↗

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[Advances in elucidating the pathophysiology and targeting therapy to treat Niemann-Pick type C disease].Semantic proximity Read ↗

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Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts.Semantic proximity Read ↗

Overview of clinical, molecular, and therapeutic features of Niemann-Pick disease (types A, B, and C): Focus on therapeutic approaches.Semantic proximity Read ↗

Chronic administration of an HDAC inhibitor treats both neurological and systemic Niemann-Pick type C disease in a mouse model.Semantic proximity Read ↗

PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2.Semantic proximity Read ↗

Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells.Semantic proximity Read ↗

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