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Article

Exome sequencing and in vitro studies identified podocalyxin as a candidate gene for focal and segmental glomerulosclerosis.

Kidney international - 1 Jan 2014

Barua Moumita, Shieh Eric, Schlondorff Johannes, Genovese Giulio, Kaplan Bernard S, Pollak Martin R

Abstract excerpt

Our understanding of focal and segmental glomerulosclerosis (FSGS) has advanced significantly from the studies of rare, monogenic forms of the disease. These studies have demonstrated the critical roles of multiple aspects of podocyte function in maintaining glomerular function. A substantial body of research has suggested that the integral membrane protein podocalyxin (PODXL) is required for proper functioning...

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Identifiers

PMID: 24048372
DOI: 10.1038/ki.2013.354
PMCID: PMC4068013

Genes

PODXL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Exome sequencing and in vitro studies identified podocalyxin as a candidate gene for focal and segmental glomerulosclerosis.PMID 24048372Read ↗

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