Article
Identical effects of VEGF and serum-deprivation on phenotype and function of adipose-derived stromal cells from healthy donors and patients with ischemic heart disease.
Journal of translational medicine - 18 Sept 2013
Follin Bjarke, Tratwal Josefine, Haack-Sørensen Mandana, Elberg Jens Jørgen, Kastrup Jens, Ekblond Annette
Abstract excerpt
BACKGROUND: Adipose-derived stromal cells (ASCs) stimulated with vascular endothelial growth factor (VEGF) and serum-deprived, are applied in the first in-man double-blind placebo-controlled MyStromalCell Trial, as a novel therapeutic option for treatment of ischemic heart disease (IHD). This in vitro study explored the effect of VEGF and serum deprivation on endothelial differentiation capacity of ASCs from...
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