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Ranking and selection of MII oocytes in human ICSI cycles using gene expression levels from associated cumulus cells

15 Sept 2013

Abstract excerpt

STUDY QUESTION: Can the ranked expression levels of a cohort of cumulus cell (CC) genes be used to select MII oocytes with a potential for blastocyst development and live birth? SUMMARY ANSWER: A ranking method containing four (HAS2, FSHR, VCAN, PR) of the eight genes evaluated in this study for identifying good quality MII oocytes provides a significantly better outcome compared with random selection and is...

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PMID: 24041818
DOI: 10.1093/humrep/det357

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