Article
Elderly age is not a negative predictive factor for virological response to therapy with pegylated interferon-α and ribavirin in chronic hepatitis C virus patients.
Liver international : official journal of the International Association for the Study of the Liver - 1 Apr 2014
Frei Pascal, Leucht Anna-Kathrin, Held Ulrike, Kofmehl Reto, Manser Christine N, Schmitt Johannes, Mertens Joachim, Rau Monika, Baur Katharina, Gerlach Tilman, Negro Francesco, Heim Markus, Moradpour Darius, Cerny Andreas, Dufour Jean-François, Müllhaupt Beat, Geier Andreas
Abstract excerpt
BACKGROUND & AIMS: Age is frequently discussed as negative host factor to achieve a sustained virological response (SVR) to antiviral therapy of chronic hepatitis C. However, elderly patients often show advanced fibrosis/cirrhosis as known negative predictive factor. The aim of this study was to assess age as an independent predictive factor during antiviral therapy. METHODS: Overall, 516 hepatitis C patients...
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