Article
Vaccine-associated enhanced respiratory disease does not interfere with the adaptive immune response following challenge with pandemic A/H1N1 2009.
Viral immunology - 1 Oct 2013
Gauger Phillip C, Loving Crystal L, Lager Kelly M, Janke Bruce H, Kehrli Marcus E, Roth James A, Vincent Amy L
Abstract excerpt
The implications of sequential prime and challenge with mismatched influenza A viruses is a concern in mammals, including humans. We evaluated the ability of pigs affected with vaccine-associated enhanced respiratory disease (VAERD) to generate a humoral immune response against the heterologous challenge virus inciting the VAERD. Vaccinated and challenged (V/C) pigs were administered an inactivated swine...
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