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Article

In vitro replication competence of a hepatitis B genotype D/A recombinant virus: dissimilar biological behaviour regarding its parental genotypes.

The Journal of general virology - 1 Dec 2013

Trinks Julieta, Sugiyama Masaya, Tanaka Yasuhito, Kurbanov Fuat, Benetucci Jorge, Giménez Edgardo, Weissenbacher Mercedes C, Mizokami Masashi, Oubiña José R

Abstract excerpt

Hepatitis B virus (HBV) DNA recombinants contribute to ~30% of the overall full-length sequences already deposited in GenBank. However, their biological behaviour has not been analysed so far. In this study, the in vitro replication kinetics of the first D/A recombinant from the American continent differed from its parental genotypes, exhibiting higher extracellular levels of HBV DNA and hepatitis B e antigen....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B, Chronic

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Share to Recombination, Genetic

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Identifiers

PMID: 24026673
DOI: 10.1099/vir.0.053595-0

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