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Article

Utility of ATP7B in prediction of response to platinum-based chemotherapy in urothelial bladder cancer.

Anticancer research - 1 Sept 2013

Schmid Sebastian Christoph, Schuster Tibor, Horn Thomas, Gschwend Jürgen, Treiber Uwe, Weirich Gregor

Abstract excerpt

BACKGROUND: Platinum-based chemotherapy is the treatment of choice for metastatic urothelial carcinoma, which is limited by primary and secondary resistance of the tumour. The Cu(2+) transporting beta polypeptide ATPase (ATP7B) is believed to play a role in this resistance. The aim of this study was to screen the ATP7B gene for mutations and loss of heterozygosity in bladder cancer and to evaluate their impact on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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PMID: 24023303

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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