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Article

Pharmacogenetics of ABC and SLC transporters in metastatic colorectal cancer patients receiving first-line FOLFIRI treatment.

Pharmacogenetics and genomics - 1 Oct 2013

De Mattia Elena, Toffoli Giuseppe, Polesel Jerry, D'Andrea Mario, Corona Giuseppe, Zagonel Vittorina, Buonadonna Angela, Dreussi Eva, Cecchin Erika

Abstract excerpt

OBJECTIVE: Membrane transporters are widely recognized as important determinants of drug disposition and response, generating increasing interest on the pharmacological implications of their genetic variations. The aim of this study was to elucidate the predictive/prognostic role of ATP-binding cassette (ABC) and solute carrier (SLC) protein polymorphisms on irinotecan (FOLFIRI regimen) outcome. PATIENTS AND...

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Share to ATP-Binding Cassette Transporters
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24018773
DOI: 10.1097/FPC.0b013e328364b6cf

Genes

ABCG2
ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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