Familial predisposition to renal disease in two generations of Pima Indians with type 2 (non-insulin-dependent) diabetes mellitus.

doi:10.1007/BF00404096

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Article

Familial predisposition to renal disease in two generations of Pima Indians with type 2 (non-insulin-dependent) diabetes mellitus.

Diabetologia - 1 Jul 1990

Pettitt D J, Saad M F, Bennett P H, Nelson R G, Knowler W C

Abstract excerpt

We studied the occurrence of renal disease by measuring serum creatinine and urine protein concentrations in the diabetic members of 316 Pima Indian families with Type 2 (non-insulin-dependent) diabetes in two successive generations to determine if diabetic renal disease aggregates in families. After adjustment for sex and other risk factors, proteinuria occurred among 14.3% of the diabetic offspring if neither...

Topics

Adult
Arizona
Blood Pressure
Creatinine
Diabetes Mellitus, Type 2
Diabetic Nephropathies
Family
Female
Genetic Predisposition to Disease
Humans
Indians, North American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Longitudinal Studies

Male

Middle Aged

Prevalence

Proteinuria

Regression Analysis

Source

Open in PubMed

Identifiers

PMID: 2401399
DOI: 10.1007/BF00404096

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2401399-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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