Article
Marked and persistent eosinophilia in the absence of clinical manifestations.
The Journal of allergy and clinical immunology - 1 Apr 2014
Chen Yun-Yun K, Khoury Paneez, Ware JeanAnne M, Holland-Thomas Nicole C, Stoddard Jennifer L, Gurprasad Shakuntala, Waldner Amy J, Klion Amy D
Abstract excerpt
BACKGROUND: Although most patients with hypereosinophilic syndromes (HES) present with clinical signs and symptoms attributable to eosinophilic tissue infiltration, some untreated patients remain asymptomatic or have signs and symptoms, such as allergic rhinitis, for which the relationship to peripheral eosinophilia is unclear (hypereosinophilia of unknown significance [HEUS]). OBJECTIVE: To identify and...
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