[Possible role of genetic factors on reduced risk for gastric cancer among duodenal ulcer patients].

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[Possible role of genetic factors on reduced risk for gastric cancer among duodenal ulcer patients].

Nihon rinsho. Japanese journal of clinical medicine - 1 Aug 2013

Matsuda Koichi, Tanikawa Chizu, Nakamura Yusuke

Abstract excerpt

Although H. pylori causes both gastric cancer and peptic ulcer, duodenal ulcer patients were known to have low risk for gastric cancer. Recently the association of PSCA and ABO with duodenal ulcer were identified by GWAS in the Japanese population. A T-allele of SNP rs2294008 in the PSCA promoter creates the upstream translational initiation codon and affects the protein localization from cytoplasm to cell...

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Identifiers

PMID: 23967685

Genes

PSCA
ABO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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