Article
Effects of ACE I/D polymorphism and aerobic training on the immune-endocrine network and cardiovascular parameters of postmenopausal women.
The Journal of clinical endocrinology and metabolism - 1 Oct 2013
Izzicupo Pascal, Ghinassi Barbara, D'Amico Maria Angela, Di Blasio Andrea, Gesi Marco, Napolitano Giorgio, Gallina Sabina, Di Baldassarre Angela
Abstract excerpt
CONTEXT: Estrogen deficiency, systemic low-grade inflammation, and reduction of adrenal gland function have central roles in noncommunicable chronic disease (NCD) development. With angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism, the deletion variant (DD) is related to higher levels of circulating angiotensin II than I allele carriers (II/ID), which might interact with all of these...
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