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Article

Integration of Autophagy and Anoikis Resistance in Solid Tumors

20 Aug 2013

Abstract excerpt

Macroautophagy or autophagy is a lysosome-dependent process in which enzymatic degradation and recycling of cytosolic components occurred due to stressful conditions. This cellular arrangement imparts anoikis resistance in solid tumors. Anoikis, a special form of apoptosis occurring when cells detach from the extracellular matrix, is a critical mechanism in maintaining tissue homeostasis and development. Anoikis...

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PMID: 23963853
DOI: 10.1002/ar.22769

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