Novel ctxB variants of Vibrio cholerae O1 isolates, China.

doi:10.1016/j.meegid.2013.08.004

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Article

Novel ctxB variants of Vibrio cholerae O1 isolates, China.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2013

Zhang Ping, Zhou Haijian, Kan Biao, Wang Duochun

Abstract excerpt

We screened 650 isolates from historical collection of Vibrio cholerae O1 during the 7th cholera pandemic in China, by amplifying and sequencing the cholera toxin subunit gene ctxB. Ten isolates were identified as harboring three novel ctxB genotypes based on amino acid residue substitutions. Within them one isolate from a patient in 1964 was similar to the El Tor genotype, except for an 11 amino acid repeat...

Topics

Amino Acid Sequence
Bacterial Proteins
Bacterial Typing Techniques
Base Sequence
China
Cholera
Cholera Toxin
DNA, Bacterial
Disease Outbreaks
Genetic Variation
Genotype
Humans
Molecular Sequence Data
Repressor Proteins
Sequence Alignment
Sequence Analysis, DNA
Vibrio cholerae O1

Source

Open in PubMed

Identifiers

PMID: 23954417
DOI: 10.1016/j.meegid.2013.08.004

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