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MTB-3, a microtubule plus-end tracking protein (+TIP) of Neurospora crassa.

PloS one - 1 Jan 2013

Mouriño-Pérez Rosa R, Linacre-Rojas Lorena P, Román-Gavilanes Ariana I, Lew Thomas K, Callejas-Negrete Olga A, Roberson Robert W, Freitag Michael

Abstract excerpt

The microtubule (MT) "plus end" constitutes the platform for the accumulation of a structurally and functionally diverse group of proteins, collectively called "MT plus-end tracking proteins" (+TIPs). +TIPs control MT dynamics and link MTs to diverse sub-cellular structures. Neurospora crassaMicroTubule Binding protein-3 (MTB-3) is the homolog of yeast EB1, a highly conserved +TIP. To address the function of...

Topics

Actins
Carrier Proteins
Fungal Proteins
Hyphae
Microtubules
Molecular Motor Proteins
Mutation
Neurospora crassa
Phenotype
Protein Transport
Recombinant Fusion Proteins

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PMID: 23950979
DOI: 10.1371/journal.pone.0070655
PMCID: PMC3741187

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