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Article

Two cases of placental T21 mosaicism: challenging the detection limits of non‐invasive prenatal testing

8 Aug 2013

Abstract excerpt

What's already known about this topic? Confined placental mosaicism (CPM) is a known biological phenomenon that can lead to false positive non-invasive prenatal test results. The small number of false negative non‐invasive prenatal test results reported to date are believed to be because of a low fetal DNA fraction in maternal plasma and/or placental mosaicism What does this study add? The degree and...

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Share to Fetal and Pediatric Neurological Disorders
Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics

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PMID: 23929588
DOI: 10.1002/pd.4212

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