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Article

Association of telomere shortening in myocardium with heart weight gain and cause of death

9 Aug 2013

Abstract excerpt

We attempted to clarify myocardial telomere dynamics using samples from 530 autopsied patients using Southern blot analysis. Overall regression analysis demonstrated yearly telomere reduction rate of 20 base pairs in the myocardium. There was a significant correlation between myocardial telomere and aging. Moreover, regression analyses of telomere and heart weight yielded a telomere reduction rate of 3 base pairs...

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Identifiers

PMID: 23929129
DOI: 10.1038/srep02401

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