Article
Occupational trichloroethylene hypersensitivity syndrome: human herpesvirus 6 reactivation and rash phenotypes.
Journal of dermatological science - 1 Dec 2013
Kamijima Michihiro, Wang Hailan, Yamanoshita Osamu, Ito Yuki, Xia Lihua, Yanagiba Yukie, Chen Cishan, Okamura Ai, Huang Zhenlie, Qiu Xinxiang, Song Xiangrong, Cai Tingfeng, Liu Lili, Ge Yichen, Deng Yingyu, Naito Hisao, Yoshikawa Tetsushi, Tohyama Mikiko, Li Laiyu, Huang Hanlin, Nakajima Tamie
Abstract excerpt
BACKGROUND: Trichloroethylene (TCE) is an industrial solvent which can cause severe generalized dermatitis, i.e., occupational TCE hypersensitivity syndrome. Reactivation of latent human herpesvirus 6 (HHV6) can occur in such patients, which has made TCE known as a causative chemical of drug-induced hypersensitivity syndrome (DIHS). OBJECTIVE: This study aimed to clarify HHV6 status, cytokine profiles and their...
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