Article
Effects of MTHFR gene polymorphism on the clinical and electrophysiological characteristics of migraine.
BMC neurology - 5 Aug 2013
Azimova Julia E, Sergeev Alexey V, Korobeynikova Liubov A, Kondratieva Natalia S, Kokaeva Zarema G, Shaikhaev Gadji O, Skorobogatykh Kirill V, Fokina Natalia M, Tabeeva Gyusal R, Klimov Eugene A
Abstract excerpt
BACKGROUND: It was previously shown that the MTHFR gene polymorphism correlated with an increased risk of migraine, particularly migraine with aura. The substitution of cytosine for thymine at the position 677 of the MTHFR gene leads to formation of the thermolabile form of the protein and development of hyperhomocysteinemia, which increases the probability of migraine. The purpose of this study was to determine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.