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Article

Assessing the bioconfinement potential of a Nicotiana hybrid platform for use in plant molecular farming applications.

BMC biotechnology - 6 Aug 2013

Rice J Hollis, Mundell Richard E, Millwood Reginald J, Chambers Orlando D, Stewart C Neal, Davies H Maelor

Abstract excerpt

BACKGROUND: The introduction of pharmaceutical traits in tobacco for commercial production could benefit from the utilization of a transgene bioconfinement system. It has been observed that interspecific F1Nicotiana hybrids (Nicotiana tabacum × Nicotiana glauca) are sterile and thus proposed that hybrids could be suitable bioconfined hosts for biomanufacturing. We genetically tagged hybrids with green fluorescent...

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Identifiers

PMID: 23914736
DOI: 10.1186/1472-6750-13-63
PMCID: PMC3750662

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Source receipt: pubmed, retrieved 7 Sept 2026.

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