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Article

In vitro evolution of an archetypal enteropathogenic Escherichia coli strain.

Journal of bacteriology - 1 Oct 2013

Nisa Shahista, Hazen Tracy H, Assatourian Lillian, Nougayrède Jean-Philippe, Rasko David A, Donnenberg Michael S

Abstract excerpt

Enteropathogenic Escherichia coli (EPEC) is a leading cause of infantile diarrhea in developing countries. EPEC strain E2348/69 is used worldwide as a prototype to study EPEC genetics and disease. However, isolates of E2348/69 differ phenotypically, reflecting a history of in vitro selection. To identify the genomic and phenotypic changes in the prototype strain, we sequenced the genome of the nalidixic...

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Identifiers

PMID: 23913321
DOI: 10.1128/JB.00704-13
PMCID: PMC3807458

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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