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Article

Twin studies and the genetics of Parkinson's disease—a reappraisal

1 Jan 1990

Abstract excerpt

Parkinson's disease (PD) has long been regarded as having a hereditary component. However, three recent twin studies have been interpreted as excluding any significant genetic component in the etiology of PD. In this article, we reexamine these twin studies and argue that such a conclusion is premature. We review statistical tests of twin concordance rates, including calculation of G, the coefficient of genetic...

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PMID: 2388635
DOI: 10.1002/mds.870050302

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