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Towards Clinical Molecular Diagnosis of Inherited Cardiac Conditions: A Comparison of Bench-Top Genome DNA Sequencers

4 Jul 2013

Abstract excerpt

BACKGROUND: Molecular genetic testing is recommended for diagnosis of inherited cardiac disease, to guide prognosis and treatment, but access is often limited by cost and availability. Recently introduced high-throughput bench-top DNA sequencing platforms have the potential to overcome these limitations. METHODOLOGY/PRINCIPAL FINDINGS: We evaluated two next-generation sequencing (NGS) platforms for molecular...

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PMID: 23861798
DOI: 10.1371/journal.pone.0067744

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