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Article

Association of tyrosyl-DNA phosphodiesterase 1 polymorphism with Tourette syndrome in Taiwanese patients.

Journal of clinical laboratory analysis - 1 Jul 2013

Wu Bor-Tsang, Lin Wei-Yong, Chou I-Ching, Liu Hsin-Ping, Lee Cheng-Chun, Tsai Yuhsin, Wu Wan-Chen, Tsai Fuu-Jen

Abstract excerpt

BACKGROUND: Genetic, environmental, immunological, and hormonal factors contribute to the etiology of Tourette syndrome (TS). From the genetic standpoint, TS is a heterogeneous disorder. In our previous study, we found that a single nucleotide polymorphism (SNP) of x-ray repair cross-complementing group 1 (XRCC1), a DNA repair gene, was associated with TS. Previous studies also showed that tyrosyl-DNA...

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Source

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Identifiers

PMID: 23852793
DOI: 10.1002/jcla.21606
PMCID: PMC6807418

Genes

TDP1
XRCC1

Variants

rs28365054

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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