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Article

Pharmacogenomics in early-phase clinical development.

Pharmacogenomics - 1 Jul 2013

Burt Tal, Dhillon Savita

Abstract excerpt

Pharmacogenomics (PGx) offers the promise of utilizing genetic fingerprints to predict individual responses to drugs in terms of safety, efficacy and pharmacokinetics. Early-phase clinical trial PGx applications can identify human genome variations that are meaningful to study design, selection of participants, allocation of resources and clinical research ethics. Results can inform later-phase study design and...

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Identifiers

PMID: 23837482
DOI: 10.2217/pgs.13.81
PMCID: PMC4551460

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