Article
IL-10 produced by trophoblast cells inhibits phagosome maturation leading to profound intracellular proliferation of Salmonella enterica Typhimurium.
Placenta - 1 Sept 2013
Nguyen T, Robinson N, Allison S E, Coombes B K, Sad S, Krishnan L
Abstract excerpt
INTRODUCTION: Salmonella enterica Typhimurium (ST) is a phagosomal pathogen that can infect placental trophoblast cells leading to abortion and severe maternal illness. It is unclear how the trophoblast cells promote profound bacterial proliferation. METHODS: The mechanism of internalization, int...
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