Article
Phase II randomized trial comparing high-dose IFN-α2b with temozolomide plus cisplatin as systemic adjuvant therapy for resected mucosal melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2013
Lian Bin, Si Lu, Cui Chuanliang, Chi Zhihong, Sheng Xinan, Mao Lili, Li Siming, Kong Yan, Tang Bixia, Guo Jun
Abstract excerpt
PURPOSE: Mucosal melanoma is rare and associated with extremely poor prognosis. However, standard adjuvant therapy for mucosal melanoma has not been established. We conducted a randomized phase II clinical trial in patients with resected mucosal melanoma to compare the efficacy and safety of high-dose IFN-α2b (HDI) and temozolomide-based chemotherapy as adjuvant therapy. EXPERIMENTAL DESIGN: Patients with mucosal...
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