Article
Splenectomy prior to antiviral therapy in patients with hepatitis C virus related decompensated cirrhosis.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2000
Ji Fanpu, Zhang Shu, Huang Na, Deng Hong, Li Zongfang
Abstract excerpt
Patients with hepatitis C virus-related decompensated cirrhosis can benefit from interferon-based antiviral therapy, but the common complication of cytopenia is a contraindication for this treatment. Splenectomy prior to interferon therapy may alleviate this problem. To investigate whether splenectomy improves the efficacy of antiviral therapy, 13 interferon-naïve hepatitis C virus decompensated cirrhotic...
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