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Article

Influence of polymorphisms in ERCC5, XPA and MTR DNA repair and synthesis genes in B-cell lymphoma risk. A case-control study in Spanish population.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000

Ruiz-Cosano J, Torres-Moreno D, Conesa-Zamora P

Abstract excerpt

PURPOSE: Functions pertaining to DNA repair and synthesis are believed to play a critical role in cancer development and seem to be affected by genetic polymorphisms. Herein we performed a case-control study evaluating the influence of three single nucleotide polymorphisms (SNPs) in XPA, ERCC5 and MTR [rs1800975 (G-4A), rs17655 (Asp1104His) and rs1805087 (A2756G), respectively] in lymphoma risk. METHODS: Genotype...

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Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Share to Chi-Square Distribution
Share to DNA Repair
Share to DNA Replication
Share to Endonucleases
Share to Lymphoma, B-Cell
Share to Spain
Share to Xeroderma Pigmentosum Group A Protein

Source

Identifiers

PMID: 23818366

Genes

ERCC5
MTR
XPA

Variants

rs1800975

Provenance

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