Article
EGFR tyrosine kinase inhibitors beyond focal progression obtain a prolonged disease control in patients with advanced adenocarcinoma of the lung.
Lung cancer (Amsterdam, Netherlands) - 1 Sept 2013
Conforti Fabio, Catania Chiara, Toffalorio Francesca, Duca Matteo, Spitaleri Gianluca, Barberis Massimo, Noberasco Cristina, Delmonte Angelo, Santarpia Mariacarmela, Lazzari Chiara, De Pas Tommaso Martino
Abstract excerpt
INTRODUCTION: Recent data show that EGFR pathway and its inhibition maintain their role after progression of disease during EGFR TKI therapy in NSCLCs. We conducted a retrospective study with the aim of evaluating efficacy and feasibility of prosecution of EGFR TKI therapy beyond focal progression associated to locoregional radiotherapy. METHODS: We retrospectively analyzed the data of all NSCLC patients treated...
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