Article
Sequencing analysis of the ATOH7 gene in individuals with optic nerve hypoplasia.
Ophthalmic genetics - 1 Mar 2014
Lim Sing-Hui, St Germain Elizabeth, Tran-Viet Khanh-Nhat, Staffieri Sandra, Marino Meghan, Dollfus Pr Hélène, Nading Erica B, Crowe Sue, Gole Glen, Perdomo-Trujillo Yaumara, Haybittel Michael, Elder James, Pelletier Valérie, Traboulsi Elias, Mackey David, Young Terri L
Abstract excerpt
BACKGROUND: The Atonal Homolog 7 (ATOH7) gene has been implicated in association studies with optic nerve head diameter size. Hence, we screened optic nerve hypoplasia (ONH) patient DNA samples from Australia, France, and the United States for sequence variants in theATOH7 gene using Sanger sequencing. METHODS: Sanger sequencing of theATOH7 gene was performed on 34 affected individual DNA samples. Sequencing was...
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