Article
The influence of ageing on the development and management of rheumatoid arthritis.
Nature reviews. Rheumatology - 1 Oct 2013
Boots Annemieke M H, Maier Andrea B, Stinissen Piet, Masson Pierre, Lories Rik J, De Keyser Filip
Abstract excerpt
The population of elderly individuals with rheumatoid arthritis (RA) is expanding, due mainly to increasing life expectancy. A variety of theories have been proposed to explain the ageing process, including accumulation of DNA damage and resultant changes in biological processes. Such changes can influence the development and/or course of disease. Furthermore, alterations in biological function determine the...
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