Article
Histologic findings of femoral heads from patients with Gaucher disease treated with enzyme replacement.
American journal of clinical pathology - 1 Jul 2013
Lebel Ehud, Elstein Deborah, Peleg Ariel, Reinus Constantine, Zimran Ari, Amir Gail
Abstract excerpt
OBJECTIVES: To assess correlations of patient demographics, including enzyme replacement therapy (ERT) with bone histology, to facilitate decisions of whether and when to perform hip replacement surgery in patients with Gaucher disease. METHODS: We examined the histology of surgically removed femoral heads and categorized findings by the presence or extent of osteonecrosis, Gaucher cell (GC) infiltration, and...
Read the complete abstract on PubMedTopics
- Adolescent
- Adult
- Aged
- Bone Regeneration
- Enzyme Replacement Therapy
- Female
- Femur Head