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Article

Network topologies and convergent aetiologies arising from deletions and duplications observed in individuals with autism.

PLoS genetics - 1 Jun 2013

Noh Hyun Ji, Ponting Chris P, Boulding Hannah C, Meader Stephen, Betancur Catalina, Buxbaum Joseph D, Pinto Dalila, Marshall Christian R, Lionel Anath C, Scherer Stephen W, Webber Caleb

Abstract excerpt

Autism Spectrum Disorders (ASD) are highly heritable and characterised by impairments in social interaction and communication, and restricted and repetitive behaviours. Considering four sets of de novo copy number variants (CNVs) identified in 181 individuals with autism and exploiting mouse functional genomics and known protein-protein interactions, we identified a large and significantly interconnected...

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Source

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Identifiers

PMID: 23754953
DOI: 10.1371/journal.pgen.1003523
PMCID: PMC3675007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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