Article
Candidate genes and genetic architecture of symbiotic and agronomic traits revealed by whole-genome, sequence-based association genetics in Medicago truncatula.
PloS one - 1 Jan 2013
Stanton-Geddes John, Paape Timothy, Epstein Brendan, Briskine Roman, Yoder Jeremy, Mudge Joann, Bharti Arvind K, Farmer Andrew D, Zhou Peng, Denny Roxanne, May Gregory D, Erlandson Stephanie, Yakub Mohammed, Sugawara Masayuki, Sadowsky Michael J, Young Nevin D, Tiffin Peter
Abstract excerpt
Genome-wide association study (GWAS) has revolutionized the search for the genetic basis of complex traits. To date, GWAS have generally relied on relatively sparse sampling of nucleotide diversity, which is likely to bias results by preferentially sampling high-frequency SNPs not in complete linkage disequilibrium (LD) with causative SNPs. To avoid these limitations we conducted GWAS with >6 million SNPs...
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