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Article

Oral Inoculation of Chickens with a Candidate Fowl Adenovirus 9 Vector

6 Jun 2013

Abstract excerpt

Fowl adenoviruses (FAdVs) are a potential alternative to human adenovirus-based vaccine vectors. Our previous studies demonstrated that a 2.4-kb region at the left end of the FAdV-9 genome is nonessential for virus replication and is suitable for the insertion or replacement of transgenes. Our in vivo study showed that the virus FAdV-9Δ4, lacking six open reading frames (ORFs) at the left end of its genome,...

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PMID: 23740924
DOI: 10.1128/cvi.00187-13

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