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Article

Global transcriptional and phenotypic analyses of Escherichia coli O157:H7 strain Xuzhou21 and its pO157_Sal cured mutant.

PloS one - 1 Jan 2013

Zhao Hongqing, Chen Chen, Xiong Yanwen, Xu Xuefang, Lan Ruiting, Wang Haiyin, Yao Xinyue, Bai Xiangning, Liu Xuetong, Meng Qiong, Zhang Xiaoai, Sun Hui, Zhao Ailan, Bai Xuemei, Cheng Yuli, Chen Qiang, Ye Changyun, Xu Jianguo

Abstract excerpt

Escherichia coli O157:H7 is an important food-borne pathogen that can cause hemorrhagic colitis and hemolytic-uremic syndrome in humans. pO157_Sal, a novel conjugative plasmid is present in a Chinese O157:H7 outbreak strain Xuzhou21. Here we investigated the phenotypic and transcriptional differences between the wild type strain Xuzhou21 and the pO157_Sal cured mutant strain Xuzhou21m. RNA-Seq analysis found that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23738017
DOI: 10.1371/journal.pone.0065466
PMCID: PMC3667801

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