Article
XRCC1 codon 280 polymorphism and susceptibility to lung cancer: a meta-analysis of the literatures.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2013
Guo Qin-xiang, Yang Wei-hua, Zhai Jin-fang, Han Fu-cai, Wang Chun-yan
Abstract excerpt
The X-ray repair cross-complementation group 1 (XRCC1) protein plays an important role in base excision repair, and the genetic polymorphisms in the XRCC1 gene influence its function. XRCC1 codon 280 polymorphism is an Arg-His change in the XRCC1 gene. Many studies were published to investigate the association between XRCC1 codon 280 polymorphism and risk of lung cancer, but the results were inconsistent. We...
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