Article
Clinicopathological significance of HuR expression in gallbladder carcinoma: with special emphasis on the implications of its nuclear and cytoplasmic expression.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2013
Sun Ding-Ping, Lin Ching-Yih, Tian Yu-Feng, Chen Li-Tzong, Lin Li-Ching, Lee Sung-Wei, Hsing Chung-Hsi, Lee Hao-Hsien, Shiue Yow-Ling, Huang Hsuan-Ying, Li Chien-Feng, Liang Peir-In
Abstract excerpt
Gallbladder carcinoma (GBC) is a relatively rare disease which pathogenesis is less clarified. Human antigen R (HuR), a RNA-binding protein, modulates the expressions of various cancer-related proteins by stabilizing or regulating the transcription of the corresponding messenger RNA. The significance of HuR expression in a large cohort with GBCs is yet to be evaluated. In total, 164 cases of GBC were selected,...
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