Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets.

American journal of respiratory and critical care medicine - 15 Oct 2013

Eckert Danny J, White David P, Jordan Amy S, Malhotra Atul, Wellman Andrew

Abstract excerpt

RATIONALE: The pathophysiologic causes of obstructive sleep apnea (OSA) likely vary among patients but have not been well characterized. OBJECTIVES: To define carefully the proportion of key anatomic and nonanatomic contributions in a relatively large cohort of patients with OSA and control subjects to identify pathophysiologic targets for future novel therapies for OSA. METHODS: Seventy-five men and women with...

Topics

Adult
Aged
Case-Control Studies
Female
Humans
Male
Middle Aged
Phenotype
Polysomnography
Respiratory Muscles
Respiratory System

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sleep Apnea, Obstructive

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 23721582
DOI: 10.1164/rccm.201303-0448OC
PMCID: PMC3826282

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-23721582-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets.PMID 23721582Read ↗

The physiological phenotype of obstructive sleep apnea differs between Caucasian and Chinese patientsSemantic proximity Read ↗

Obstructive sleep apnea in older adults is a distinctly different physiological phenotype.Semantic proximity Read ↗

Phenotypic approaches to obstructive sleep apnoea - New pathways for targeted therapy.Semantic proximity Read ↗

Understanding Phenotypes of Obstructive Sleep Apnea: Applications in Anesthesia, Surgery, and Perioperative Medicine.Semantic proximity Read ↗

Vulnerability to Postoperative Complications in Obstructive Sleep Apnea: Importance of Phenotypes.Semantic proximity Read ↗

Phenotypes of Obstructive Sleep Apnea.Semantic proximity Read ↗

Phenotypes in obstructive sleep apnea: A definition, examples and evolution of approaches.Semantic proximity Read ↗

Phenotyping the pathophysiology of obstructive sleep apnea using polygraphy/polysomnography: a review of the literature.Semantic proximity Read ↗

Differences in Endotypic Traits Between Obstructive Sleep Apnoea Patients With and Without Excessive Daytime Sleepiness.Semantic proximity Read ↗

Sex-specific age-related worsening of pathological endotypic traits in patients with obstructive sleep apnea.Semantic proximity Read ↗

Qualitative Phenotyping of Obstructive Sleep Apnea and Its Clinical Usefulness for the Sleep Specialist.Semantic proximity Read ↗

Research Priorities for Translating Endophenotyping of Adult Obstructive Sleep Apnea to the Clinic: An Official American Thoracic Society Research Statement.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.