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Genome-wide association study identifies loci affecting blood copper, selenium and zinc.

Human molecular genetics - 1 Oct 2013

Evans David M, Zhu Gu, Dy Veronica, Heath Andrew C, Madden Pamela A F, Kemp John P, McMahon George, St Pourcain Beate, Timpson Nicholas J, Golding Jean, Lawlor Debbie A, Steer Colin, Montgomery Grant W, Martin Nicholas G, Smith George Davey, Whitfield John B

Abstract excerpt

Genetic variation affecting absorption, distribution or excretion of essential trace elements may lead to health effects related to sub-clinical deficiency. We have tested for allelic effects of single-nucleotide polymorphisms (SNPs) on blood copper, selenium and zinc in a genome-wide association study using two adult cohorts from Australia and the UK. Participants were recruited in Australia from twins and their...

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PMID: 23720494
DOI: 10.1093/hmg/ddt239
PMCID: PMC3766178

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