Article
96-Week resistance analyses of rilpivirine in treatment-naive, HIV-1-infected adults from the ECHO and THRIVE Phase III trials.
Antiviral therapy - 1 Jan 2013
Rimsky Laurence, Van Eygen Veerle, Hoogstoel Annemie, Stevens Marita, Boven Katia, Picchio Gaston, Vingerhoets Johan
Abstract excerpt
BACKGROUND: In the ECHO/THRIVE 96-week efficacy analysis, the response rate was 78% with rilpivirine (RPV) and efavirenz (EFV) plus two nucleoside/nucleotide reverse transcriptase inhibitors. METHODS: For resistance analyses, virological failures (VFs) were genotyped and/or phenotyped at baseline and failure. RESULTS: In the overall 96-week resistance analyses, the proportion of VFs was higher with RPV (96/686,...
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