Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple trichoepitheliomas associated with a novel heterozygous mutation in the CYLD gene as an adjunct to the histopathological diagnosis.

The American Journal of dermatopathology - 1 Jun 2013

Reuven Bergman, Margarita Indelman, Dov Hershkovitz, Ziad Khamaysi

Abstract excerpt

Multiple trichoepitheliomas (TEs), especially in the familial setting, have been associated with germline heterozygous mutations in the CYLD gene. Heterozygous germline CYLD mutations and loss of heterozygosity of the CYLD gene in the TE tumor cells have been recently demonstrated in some of the multiple TE cases irrespective of a family history. The histopathological differential diagnosis of TE from basal cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Deubiquitinating Enzyme CYLD
Share to Frameshift Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Neoplastic Syndromes, Hereditary

Share to Predictive Value of Tests

Share to Skin Neoplasms

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 23694822
DOI: 10.1097/DAD.0b013e31827132af

Genes

CYLD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple trichoepitheliomas associated with a novel heterozygous mutation in the CYLD gene as an adjunct to the histopathological diagnosis.PMID 23694822Read ↗

Multiple familial trichoepithelioma with a novel mutation of the CYLD gene.Semantic proximity Read ↗

Multiple trichoepitheliomas--a novel mutation in the CYLD gene.Semantic proximity Read ↗

Novel and recurrent germline and somatic mutations in a cohort of 67 patients from 48 families with Brooke-Spiegler syndrome including the phenotypic variant of multiple familial trichoepitheliomas and correlation with the histopathologic findings in 379 biopsy specimens.Semantic proximity Read ↗

Multiple (familial) trichoepitheliomas: a clinicopathological and molecular biological study, including CYLD and PTCH gene analysis, of a series of 16 patients.Semantic proximity Read ↗

A novel mutation of CYLD in a Chinese family with multiple familial trichoepithelioma.Semantic proximity Read ↗

A novel nonsense mutation of the CYLD gene in a Turkish family with multiple familial trichoepithelioma.Semantic proximity Read ↗

Two novel CYLD gene mutations in Chinese families with trichoepithelioma and a literature review of 16 families with trichoepithelioma reported in China.Semantic proximity Read ↗

[Multiple familial trichoepithelioma: a new CYLD gene mutation].Semantic proximity Read ↗

Multiple Facial Trichoepitheliomas and Vulval Cysts: Extending the Phenotypic Spectrum in CYLD Cutaneous Syndrome.Semantic proximity Read ↗

A novel frameshift mutation in the cylindromatosis (CYLD) gene in a Chinese family with multiple familial trichoepithelioma.Semantic proximity Read ↗

Multiple familial trichoepithelioma: report of a Chinese family not associated with a mutation in the CYLD gene and CYLD protein expression in the trichoepithelioma tumor tissue.Semantic proximity Read ↗

A novel splicing mutation of the CYLD gene in a Taiwanese family with multiple familial trichoepithelioma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.